Palmitoyl Pentapeptide-4 Powder|Clinically Proven Anti-Wrinkle Peptide|B2B Ingredient
Source high-purity Palmitoyl Pentapeptide-4. This gold-standard anti-aging peptide delivers identical efficacy to Matrixyl™ in stimulating collagen & reducing wrinkles. For Global Brands.
Introduction: The Gold-Standard in Anti-Aging Peptides
Palmitoyl Pentapeptide-4 Powder is the scientifically recognized name for the pioneering anti-aging peptide that set the global standard for topical, signal-mediated skin rejuvenation. As a premier B2B supplier of proven active ingredients, we provide formulators with high-purity Palmitoyl Pentapeptide-4 to the originally trademarked Matrixyl™ ingredient. This clinically-validated molecule empowers the skin's natural repair processes, delivering visibly smoother, firmer, and younger-looking skin.

| Palmitoyl Pentapeptide-4 | |
| 214047-00-4 | |
| C39H75N7O10 | |
| 802.054 g/mol | |
| >= 98% (by HPLC) | |
| White to off-white fine powder | |
| 24 months under proper storage conditions. |
Mechanism of Action of Palmitoyl Pentapeptide-4
Palmitoyl Pentapeptide-4. Its innovative design combines the bioactive fragment of Procollagen I (KTTKS) with a palmitoyl fatty acid chain.
- acts as a natural shuttle, facilitating optimal dermal delivery of the peptide sequence.
- .
- [1].
- Palmitoyl Pentapeptide-4 effectively combats the visible signs of aging caused by collagen degradation.

Palmitoyl Pentapeptide-4.

- The foundational double-blind, placebo-controlled clinical study that established the efficacy of this molecule demonstrated that Palmitoyl Pentapeptide-4 significantly reduces wrinkle depth, volume, and skin roughness compared to placebo, with performance comparable to Retinol over a 4-month period [1]. This is the same study that validated the ingredient originally marketed as Matrixyl™.
- Directly addresses sagging skin by promoting the synthesis of new collagen, leading to a measurable improvement in skin firmness and elasticity.
- Effectively smoothens the appearance of fine lines, particularly around the eyes and forehead.
- A reinforced ECM supports better hydration and creates a smoother, more refined skin surface.

Palmitoyl Pentapeptide-4 Powder into your next generation of skincare heroes.
3% - 5% in the final product.
Anti-Wrinkle Serums & Concentrates
This peptide is highly soluble and stable. Incorporate it into the water phase of your emulsion at temperatures below 40℃ to preserve its activity.
Q: What is the relationship between Palmitoyl Pentapeptide-4 and Matrixyl™?
A: Palmitoyl Pentapeptide-4 is the universal scientific name for the active molecule. Matrixyl™ is a specific brand name for this ingredient. Our Palmitoyl Pentapeptide-4 is the same core molecule, manufactured to the highest standards of purity and efficacy, ensuring you receive an ingredient with identical performance and clinical backing.
Q: How does Palmitoyl Pentapeptide-4 differ from other anti-aging peptides like Hexapeptide-9 (KTTKS)?
A: Palmitoyl Pentapeptide-4 is a lipopeptide (KTTKS + Palmitoyl) designed for optimal skin penetration and targeted fibroblast signaling. Hexapeptide-9 (KTTKS) is the pure peptide fragment without the lipid carrier. The palmitoyl chain in Palmitoyl Pentapeptide-4 is crucial for its enhanced bioavailability and efficacy in topical formulations.
A: For clinically-substantiated results, a concentration of 3% to 5% Palmitoyl Pentapeptide-4 in the final formulation is recommended.
A: Absolutely. We provide a comprehensive Certificate of Analysis (COA) with every batch, along with a detailed Product Specification Sheet. These documents are essential for your compliance files in major markets like the EU, USA, and Asia.
Access the gold-standard anti-aging efficacy of Palmitoyl Pentapeptide-4 directly from a reliable B2B source. Build your brand on science, not just branding.
Contact Us Today to request a technical data sheet, current pricing, and a sample. E-mail: ella.zhang@huilinbio-tech.com.
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